hs-C-reactive protein as an indicator for prognosis in acute myocardial infarction

Abstract

Aims and objectives: The objective of this study is to find the serum high sensitivity-C-reactive protein (hs-CRP) in acute myocardial infarction patients at the time of admission and their association with in - hospital mortality and morbidity. Materials and Methods: A total of 50 patients of acute myocardial patients followed-up for 7 days in hospital with admission of serum hs-CRP levels. Slide agglutination was used to find the serum hs-CRP levels for qualitative and serial dilution method to carry out the semi-quantitative titration. Results: Among 50 Acute myocardial infarction (AMI) patients, 45 patients had an elevated hs-CRP and five patients had minimal or lower level of hs-CRP on the time of admission. On follow-up for 7 days, 35 out of 45 who had elevated hs-C-CRP developed vascular complications such as left ventricular failure, cardiogenic shock, ventricular ectopy, atrio-ventricular block etc. A total of 5 patients who had a minimal or low level of hs-CRP at the time of admission didn′t develop any kind of complication during their hospital stay. Conclusion: Higher the serum hs-CRP levels at the time of admission in patients with AMI greater the patients prone to develop a complication during their hospital stay.

Keywords

• Acute myocardial infarction
• high sensitivity-C-reactive protein
• left ventricular failure
• cardiogenic shock