Nature Communications (Sep 2022)

A multi-state dynamic process confers mechano-adaptation to a biological nanomachine

  • Navish Wadhwa,
  • Alberto Sassi,
  • Howard C. Berg,
  • Yuhai Tu

DOI
https://doi.org/10.1038/s41467-022-33075-5
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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Combining experiments with modeling, Wadhwa et al. propose a model for mechano-adaptation in the bacterial flagellar motor, finding that load-dependent transitions between multiple internal states govern the binding and unbinding of subunits.