Cancers (Sep 2022)

Single Cell RNA Sequencing: A New Frontier in Pancreatic Ductal Adenocarcinoma

  • Maroun Bou Zerdan,
  • Malek Shatila,
  • Dhruv Sarwal,
  • Youssef Bouferraa,
  • Morgan Bou Zerdan,
  • Sabine Allam,
  • Merima Ramovic,
  • Stephen Graziano

DOI
https://doi.org/10.3390/cancers14194589
Journal volume & issue
Vol. 14, no. 19
p. 4589

Abstract

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Pancreatic ductal adenocarcinoma is a malignancy with a high mortality rate. It exhibits significant heterogeneity in metabolic pathways which are associated with its progression. In this review, we discuss the role of single cell RNA sequencing in unraveling the metabolic and clinical features of these highly malignant tumors.

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