Large-scale gene expression profiling data of bone marrow stromal cells from osteoarthritic donors
Maik Stiehler,
Juliane Rauh,
Cody Bünger,
Angela Jacobi,
Corina Vater,
Theresa Schildberg,
Cornelia Liebers,
Klaus-Peter Günther,
Henriette Bretschneider
Affiliations
Maik Stiehler
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany; Corresponding author.
Juliane Rauh
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
Cody Bünger
Department of Orthopaedics, Aarhus University Hospital, Aarhus, Denmark
Angela Jacobi
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
Corina Vater
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
Theresa Schildberg
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
Cornelia Liebers
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
Klaus-Peter Günther
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
Henriette Bretschneider
University Centre for Orthopaedics & Trauma Surgery and Centre for Translational Bone, Joint and Soft Tissue Research, University Hospital Carl Gustav Carus at Technische Universität Dresden, Germany
This data article contains data related to the research article entitled, “in vitro characterization of bone marrow stromal cells from osteoarthritic donors” [1]. Osteoarthritis (OA) represents the main indication for total joint arthroplasty and is one of the most frequent degenerative joint disorders. However, the exact etiology of OA remains unknown. Bone marrow stromal cells (BMSCs) can be easily isolated from bone marrow aspirates and provide an excellent source of progenitor cells. The data shows the identification of pivotal genes and pathways involved in osteoarthritis by comparing gene expression patterns of BMSCs from osteoarthritic versus healthy donors using an array-based approach. Keywords: Bone marrow stroll cells, Osteoarthritis, Microarray analysis, Gene Ontology
