New Pyrimidinone Bearing Aminomethylenes and Schiff Bases as Potent Antioxidant, Antibacterial, SARS-CoV-2, and COVID-19 Main Protease MPro Inhibitors: Design, Synthesis, Bioactivities, and Computational Studies
Muhammad Sarfraz,
Muhammad Ayyaz,
Abdul Rauf,
Asma Yaqoob,
Tooba,
Muhammad Arif Ali,
Sabir Ali Siddique,
Ashfaq Mahmood Qureshi,
Muhammad Hassan Sarfraz,
Reem M. Aljowaie,
Saeedah Musaed Almutairi,
Muhammad Arshad
Affiliations
Muhammad Sarfraz
Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Muhammad Ayyaz
Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Abdul Rauf
Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Asma Yaqoob
Institute of Biochemistry, Biotechnology, and Bioinformatics. Department of Biochemistry and Molecular Biology, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Tooba
Institute of Biochemistry, Biotechnology, and Bioinformatics. Department of Biochemistry and Molecular Biology, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Muhammad Arif Ali
Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Sabir Ali Siddique
Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan
Ashfaq Mahmood Qureshi
Department of Chemistry, Government Sadiq College Women University, Bahawalpur, Pakistan
Muhammad Hassan Sarfraz
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, Botnar Institute of Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom
Reem M. Aljowaie
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
Saeedah Musaed Almutairi
Department of Botany and Microbiology, College of Science, King Saud University, Riyadh, Saudi Arabia
Muhammad Arshad
Institute of Chemistry, The Islamia University of Bahawalpur, Bahawalpur, Pakistan