Frontiers in Oncology (Sep 2017)

CASTLE Thyroid Tumor: A Case Report and Literature Review

  • Chris Lominska,
  • Christopher Fleighton Estes,
  • Prakash C. Neupane,
  • Y. Shnayder,
  • Mindi J. TenNapel,
  • Maura F. O’Neil

DOI
https://doi.org/10.3389/fonc.2017.00207
Journal volume & issue
Vol. 7

Abstract

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Carcinoma showing thymus-like differentiation is a rare tumor of the thyroid gland, which is structurally similar to thymic tissue. Overall, it has a favorable prognosis. Radiotherapy has been shown to be an effective local treatment, but there have been reports of distant recurrence. It has been suggested that adding chemotherapy may decrease the risk of recurrence. Here, we present a case report of a patient with a large tumor and extrathyroidal extension. The patient was treated with surgery, radiotherapy, and cisplatin with acceptable toxicity. The patient is free of locally recurrent or distant disease at 3 years.

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