Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
Pedro Dorado-Morales,
M. Pilar Garcillán-Barcia,
Iñigo Lasa,
Cristina Solano
Affiliations
Pedro Dorado-Morales
Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain
M. Pilar Garcillán-Barcia
Instituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria—Consejo Superior de Investigaciones Científicas, Santander, Cantabria, Spain
Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain
Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, Spain
Plasmids are major agents in the spread of antibiotic resistance genes among bacteria. How plasmids and their hosts coevolve to reduce the fitness cost associated with plasmid carriage when bacteria grow in an antibiotic-free environment is not well understood.
