The application of vicasole as a perspective nephrolithyiasis pharmacological correction’s drug

Abstract

The aim of the investigation was studying vicasole’s effect on experimental oxalate nephrolithiasis.Experimental nephrolithiasis was being modeled by using of 1% ethylenglycole’s solution as a drink for rats during 6 weeks. First group was control. In the second group since the third week was being administrated vicasole in dose 500 mkg/kg. Was being detected parameters of kidney’s function, markers enzymes activity and free oxygen’s radicals activity, was carried out morphological researches.It was concluded that vicasole’s therapy reduce experimental oxalate nephrolithiasis

Keywords

• оксалатный нефролитиаз
• викасол
• , фармакологическая коррекция