Nature Communications (Jul 2021)

Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin

  • Stephan Hirschi,
  • David Kalbermatter,
  • Zöhre Ucurum,
  • Thomas Lemmin,
  • Dimitrios Fotiadis

DOI
https://doi.org/10.1038/s41467-021-24429-6
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 10

Abstract

Read online

The cryo-EM structure of pentameric green-light absorbing proteorhodopsin together with molecular dynamics simulations and functional studies provides insights into the proton translocation pathway and oligomerization, and a protonation-dependent mechanism for intracellular half channel hydration.