Case Reports in Medicine (Jan 2011)

Episcleritis Related to Drug-Induced Lupus Erythematosus following Infliximab Therapy: A Case Report

  • Irini P. Chatziralli,
  • Evgenia Kanonidou,
  • Alexandros Chatzirallis,
  • Prodromos Dimitriadis,
  • Petros Keryttopoulos

DOI
https://doi.org/10.1155/2011/696285
Journal volume & issue
Vol. 2011

Abstract

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Drug-induced lupus erythematosus is defined as a lupus-like syndrome temporally related to continuous drug exposure which resolves after discontinuation of the offending drug. Herein, we describe a patient with distinct clinical manifestations of anti-TNF-associated DILE related to infliximab therapy. The patient exhibited clinical and laboratory findings of lupus-like illnesses as well as ocular disorders, such as episcleritis. The main message is that the symptoms of DILE should not be overlooked, although sometimes other systematic conditions may underlie them. As a result, it is very important for the clinicians to evaluate the symptoms of DILE and manage appropriately these cases.