Mediators of Inflammation (Jan 2002)

Cytokine secretion by decidual lymphocytes in transient hypertension of pregnancy and pre-eclampsia

  • Jacek R. Wilczyński,
  • Henryk Tchórzewski,
  • Ewa Głowacka,
  • Małgorzata Banasik,
  • Przemyslaw Lewkowicz,
  • Marian Szpakowski,
  • Krzysztof Zeman,
  • Jan Wilczyński

DOI
https://doi.org/10.1080/09629350220131962
Journal volume & issue
Vol. 11, no. 2
pp. 105 – 111

Abstract

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Background: Transient hypertension (TH) and pre-eclampsia (PE) are believed to have different patho-physiology. However, 15-25% of pregnant women initially diagnosed as having TH develop PE. To clarify the immuno-pathogenetical connections between the two syndromes, we studied the pattern of T helper cell (Th)1/Th2 cytokine balance disturbances existing inside maternal decidua in normal pregnancy (NP) and pregnancies complicated with TH and PE.