ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality

• Elena Sindram,
• Andrés Caballero-Oteyza,
• Naoko Kogata,
• Shaina Chor Mei Huang,
• Zahra Alizadeh,
• Laura Gámez-Díaz,
• Mohammad Reza Fazlollhi,
• Xiao Peng,
• Bodo Grimbacher,
• Michael Way,
• Michele Proietti

Affiliations

Elena Sindram

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany

Andrés Caballero-Oteyza

Department of Rheumatology and Clinical Immunology, Hannover Medical School, Carl-Neuberg-Str. 1, 30625 Hannover, Germany

Naoko Kogata

Cellular Signalling and Cytoskeletal Function Laboratory, The Francis Crick Institute, London NW1 1AT, UK

Shaina Chor Mei Huang

Cellular Signalling and Cytoskeletal Function Laboratory, The Francis Crick Institute, London NW1 1AT, UK

Zahra Alizadeh

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran 1419733154, Iran

Laura Gámez-Díaz

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany

Mohammad Reza Fazlollhi

Immunology, Asthma and Allergy Research Institute, Tehran University of Medical Sciences, Tehran 1419733154, Iran

Xiao Peng

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany

Bodo Grimbacher

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany

Michael Way

Cellular Signalling and Cytoskeletal Function Laboratory, The Francis Crick Institute, London NW1 1AT, UK

Michele Proietti

Institute for Immunodeficiency, Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Breisacher Straße 115, 79106 Freiburg, Germany