OEIS Complex: A Rare Case Report

Abstract

The Omphalocele, Exstrophy, Imperforate anus and Spinal defects (OEIS) complex is a rare midline defect that consists of omphalocele, bladder exstrophy, imperforate anus, spinal and genital abnormalities. The presentation varies from case to case representing the most severe form of Exostrophy Epispadias Sequence (EES). Regular prenatal visits and investigations including ultrasound is needed to diagnose this anomaly, but in this case diagnosis was delayed due to irregular antenatal visits by the patient. The aetiology is thought to be multifactorial as was in the present case which was provisionally diagnosed prenatally at 19 weeks. The foetus had classic ultrasound findings of OEIS complex which were later confirmed post expulsion with gross and infantogram features. Advanced level of radiological expertise is required to prenatally diagnose a case of OEIS complex. Depending on severity, management of such cases ranges from termination of pregnancy in severe cases to survival with surgical corrections postnatally in milder forms.

Keywords

• congenital malformation
• exstrophy
• imperforate anus
• omphalocele
• spinal defects