Total Water–Soluble Flavonoids From Lithocarpus litseifolius (Hance) Chun (Sweet Tea) Improve Glucose Homeostasis Through Multitarget Signalling in GDM Mice

Junfei Xu; Fenfang Zhang; Huanhuan Li; Pan Li; Junying Zeng; Xianjin Wu; Rong Zhou; Chunyan Yang; Juzuo Zhang

doi:10.1155/2024/1518080

Journal of Diabetes Research (Jan 2024)

Total Water–Soluble Flavonoids From Lithocarpus litseifolius (Hance) Chun (Sweet Tea) Improve Glucose Homeostasis Through Multitarget Signalling in GDM Mice

Junfei Xu,
Fenfang Zhang,
Huanhuan Li,
Pan Li,
Junying Zeng,
Xianjin Wu,
Rong Zhou,
Chunyan Yang,
Juzuo Zhang

Affiliations

Junfei Xu: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Fenfang Zhang: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Huanhuan Li: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Pan Li: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Junying Zeng: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Xianjin Wu: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Rong Zhou: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food
Chunyan Yang: Department of Obstetrics and Gynecology
Juzuo Zhang: College of Biological and Food Engineering/Key Laboratory of Research and Utilization of Ethnicinal Plant Resources of Hunan Province/Hunan Provincial Higher Education Key Laboratory of Intensive Processing Research on Mountain Ecological Food

DOI: https://doi.org/10.1155/2024/1518080
Journal volume & issue: Vol. 2024

Abstract

Read online

Conclusion: Oral administration of total water–soluble flavonoids can alleviate glucose intolerance and insulin resistance via the inhibition of liver cell apoptosis. The main active ingredients act on GAA through the signalling pathways of the AKT1 core axis.

Published in Journal of Diabetes Research

ISSN: 2314-6745 (Print); 2314-6753 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the endocrine glands. Clinical endocrinology
Website: https://onlinelibrary.wiley.com/journal/1485

About the journal