Journal of Integrative Bioinformatics (Aug 2017)

MUSTv2: An Improved De Novo Detection Program for Recently Active Miniature Inverted Repeat Transposable Elements (MITEs)

  • Ge Ruiquan,
  • Mai Guoqin,
  • Zhang Ruochi,
  • Wu Xundong,
  • Wu Qing,
  • Zhou Fengfeng

DOI
https://doi.org/10.1515/jib-2017-0029
Journal volume & issue
Vol. 14, no. 3
pp. 115 – 9

Abstract

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Miniature inverted repeat transposable element (MITE) is a short transposable element, carrying no protein-coding regions. However, its high proliferation rate and sequence-specific insertion preference renders it as a good genetic tool for both natural evolution and experimental insertion mutagenesis. Recently active MITE copies are those with clear signals of Terminal Inverted Repeats (TIRs) and Direct Repeats (DRs), and are recently translocated into their current sites. Their proliferation ability renders them good candidates for the investigation of genomic evolution.

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