Journal of Indian Academy of Oral Medicine and Radiology (Jan 2005)

Aggressive Central Giant Cell Granuloma Case Report & Review of Literature

  • C Krithika,
  • S Jayachandran

Journal volume & issue
Vol. 17, no. 1
pp. 38 – 42

Abstract

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First described by Jaffe in 1953, the Central Giant Cell Granuloma appears to be an enigmatic lesion unique to the jaws. The true nature of Central Giant Cell Granuloma remains unknown, despite considerable discussion and controversy in literature. Characteristically affecting the anterior mandibular region in women less than 30 years of age, the Central Giant Cell Granuloma exhibits a spectrum of clinical behaviour ranging from Non-Aggressive to Aggressive variants. We report one such case of Aggressive Central Giant Cell Granuloma, which presented rather atypically in a male patient over 50 years of age in the posterior mandibular region.

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