The beneficial effects of resveratrol supplementation on parasitemia, oxidative stress and serum biochemical parameters in Trypanosoma brucei infected dogs

Abstract

This study investigated the effect of resveratrol supplementation on parasitemia, oxidative stress and serum biochemical changes in the Trypanosoma brucei infected dogs. The mean pre-patent period (MPP) of infection was 5.75±0.96 (5-7) days and 9.00 ± 0.82 (8-10) days between infected un-supplemented and supplemented respectively, which differed significantly (p0.05) higher than the infected treated groups. The mean ALT of infected treated with both resveratrol and diminazene aceturate (DA) was significantly (P0.05) within the infected treated groups when compared with the control. The mean albumin and total protein were significantly (P0.05) difference. However, the total protein was significantly (PT. brucei infection, as it delays the onset of parasitemia and restores damages done to the liver and kidneys when combined with diminazene aceturate.

Keywords

• resveratrol
• supplementation
• trypanosoma brucei
• parasitemia
• oxidative stress