Plants (Jun 2023)

The Protective Role of Cranberries and Blueberries in Oral Cancer

  • César Esquivel-Chirino,
  • Mario Augusto Bolaños-Carrillo,
  • Daniela Carmona-Ruiz,
  • Ambar Lopéz-Macay,
  • Fernando Hernández-Sánchez,
  • Delina Montés-Sánchez,
  • Montserrat Escuadra-Landeros,
  • Luis Alberto Gaitán-Cepeda,
  • Silvia Maldonado-Frías,
  • Beatriz Raquel Yáñez-Ocampo,
  • José Luis Ventura-Gallegos,
  • Hugo Laparra-Escareño,
  • Claudia Patricia Mejía-Velázquez,
  • Alejandro Zentella-Dehesa

DOI
https://doi.org/10.3390/plants12122330
Journal volume & issue
Vol. 12, no. 12
p. 2330

Abstract

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Background: Oral cancer has a high prevalence worldwide, and this disease is caused by genetic, immunological, and environmental factors. The main risk factors associated with oral cancer are smoking and alcohol. Results: There are various strategies to reduce risk factors, including prevention programs as well as the consumption of an adequate diet that includes phytochemical compounds derived from cranberries (Vaccinium macrocarpon A.) and blueberries (Vaccinium corymbosum L.); these compounds exhibit antitumor properties. Results: The main outcome of this review is as follows: the properties of phytochemicals derived from cranberries were evaluated for protection against risk factors associated with oral cancer. Conclusions: The secondary metabolites of cranberries promote biological effects that provide protection against smoking and alcoholism. An alternative for the prevention of oral cancer can be the consumption of these cranberries and blueberries.

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