H-type hypertension: a key point for primary stroke prevention in China

Abstract

H-type hypertension is accompanied by elevated homocysteine （Hcy） （≥10 μmol/L） in the blood， which synergistically increases the risk of cardiovascular diseases with hypertension， especially stroke. Approximately 75% of hypertensive patients in China are H-type， which is closely associated with the characteristics of Chinese population. Early screening and diagnosis of H-type hypertension and accurate prevention and treatment are of significance. Folic acid supplementation based on blood pressure reduction can effectively reduce the risk of stroke in hypertensive patients. The effects of folic acid supplementation on stroke prevention vary among different populations. Screening patients with a higher cost-benefit ratio can significantly improve prevention and treatment efficiency. With the proposal of H-type hypertension concept， more and more related studies have been conducted， which provides valuable clues for elucidating relevant mechanisms. It is necessary to carry out further in-depth research to expand and supplement related theories of H-type hypertension.

Keywords

• h-type hypertension|homocysteine|hypertension|stroke