Unraveling the Complex Nexus of Human Papillomavirus (HPV) in Extragenital Keratinocyte Skin Tumors: A Comprehensive Analysis of Bowen’s Disease and In Situ Squamous-Cell Carcinoma

Claudio Conforti; Chiara Retrosi; Marina Agozzino; Caterina Dianzani; Ermanno Nardon; Anselmo Oliveri; Eros Azzalini; Stefania Guida; Giovanni Pellacani; Giovanni Di Lella; Franco Rongioletti; Iris Zalaudek; Serena Bonin

doi:10.3390/jcm13041091

Journal of Clinical Medicine (Feb 2024)

Unraveling the Complex Nexus of Human Papillomavirus (HPV) in Extragenital Keratinocyte Skin Tumors: A Comprehensive Analysis of Bowen’s Disease and In Situ Squamous-Cell Carcinoma

Claudio Conforti,
Chiara Retrosi,
Marina Agozzino,
Caterina Dianzani,
Ermanno Nardon,
Anselmo Oliveri,
Eros Azzalini,
Stefania Guida,
Giovanni Pellacani,
Giovanni Di Lella,
Franco Rongioletti,
Iris Zalaudek,
Serena Bonin

Affiliations

Claudio Conforti: IDI-IRCCS, Dermatological Research Hospital, 00167 Rome, Italy
Chiara Retrosi: IDI-IRCCS, Dermatological Research Hospital, 00167 Rome, Italy
Marina Agozzino: Dermatology Clinic, Maggiore Hospital, Piazza Ospitale 1, 34125 Trieste, Italy
Caterina Dianzani: Department of Plastic, Reconstructive and Cosmetic Surgery, Dermatology Section, Campus Bio-Medico University Hospital, 00128 Rome, Italy
Ermanno Nardon: Department of Medical Sciences (DSM), University of Trieste, 34149 Trieste, Italy
Anselmo Oliveri: Department of Medical Sciences (DSM), University of Trieste, 34149 Trieste, Italy
Eros Azzalini: Department of Medical Sciences (DSM), University of Trieste, 34149 Trieste, Italy
Stefania Guida: Dermatology Clinic, IRCCS San Raffaele Hospital, Vita-Salute University, 20132 Milan, Italy
Giovanni Pellacani: Dermatology Clinic, Department of Clinical Internal, Anesthesiological and Cardiovascular Sciences, Sapienza University of Rome, 00196 Rome, Italy
Giovanni Di Lella: IDI-IRCCS, Dermatological Research Hospital, 00167 Rome, Italy
Franco Rongioletti: Dermatology Clinic, IRCCS San Raffaele Hospital, Vita-Salute University, 20132 Milan, Italy
Iris Zalaudek: Dermatology Clinic, Maggiore Hospital, Piazza Ospitale 1, 34125 Trieste, Italy
Serena Bonin: Department of Medical Sciences (DSM), University of Trieste, 34149 Trieste, Italy

DOI: https://doi.org/10.3390/jcm13041091
Journal volume & issue: Vol. 13, no. 4
p. 1091

Abstract

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This comprehensive study delves into the intricate landscape surrounding the role of human papillomavirus (HPV) in extragenital keratinocyte skin tumors, specifically exploring Bowen’s disease (BD) and in situ squamous-cell carcinoma (iSCC). Through a multifaceted examination, this research study elucidates the nuanced interplay of HPV, gender dynamics, anatomical site variations, and potential implications for the etiopathogenesis of these malignancies.

Published in Journal of Clinical Medicine

ISSN: 2077-0383 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Medicine
Website: http://www.mdpi.com/journal/jcm

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Abstract

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