Design, Synthesis, and Biological Evaluation of Bimodal Glycopeptides as Inhibitors of Neurotoxic Protein Aggregation

Affiliations

Philip Ryan: Menzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia
Mingming Xu: Griffith Institute for Drug Discovery, Griffith University, Nathan 4111, Australia
Andrew K. Davey: Menzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia
George D. Mellick: Griffith Institute for Drug Discovery, Griffith University, Nathan 4111, Australia
Santosh Rudrawar: Menzies Health Institute Queensland, Griffith University, Gold Coast 4222, Australia

Abstract

Post-translational modifications (PTM) of proteins are becoming the focus of a growing base of [...]