A biodegradable hybrid inorganic nanoscaffold for advanced stem cell therapy

Letao Yang; Sy-Tsong Dean Chueng; Ying Li; Misaal Patel; Christopher Rathnam; Gangotri Dey; Lu Wang; Li Cai; Ki-Bum Lee

doi:10.1038/s41467-018-05599-2

Nature Communications (Aug 2018)

A biodegradable hybrid inorganic nanoscaffold for advanced stem cell therapy

Letao Yang,
Sy-Tsong Dean Chueng,
Ying Li,
Misaal Patel,
Christopher Rathnam,
Gangotri Dey,
Lu Wang,
Li Cai,
Ki-Bum Lee

Affiliations

Letao Yang: Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
Sy-Tsong Dean Chueng: Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
Ying Li: Department of Biomedical Engineering, Rutgers, The State University of New Jersey
Misaal Patel: Department of Biomedical Engineering, Rutgers, The State University of New Jersey
Christopher Rathnam: Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
Gangotri Dey: Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
Lu Wang: Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey
Li Cai: Department of Biomedical Engineering, Rutgers, The State University of New Jersey
Ki-Bum Lee: Department of Chemistry and Chemical Biology, Rutgers, The State University of New Jersey

DOI: https://doi.org/10.1038/s41467-018-05599-2
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 14

Abstract

Read online

The promise of stem cell therapy for treating central nervous system disease is limited by low stem cell transplantation survival rates and poorly controlled cell fate. Here, the authors develop a biodegradable nanoscaffold for spinal cord injury that enhances transplantation and differentiation of neural stem cells and delivers drugs.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

About the journal