THE VALUE OF GENETIC AND ACQUIRED THROMBOPHILIA IN THE PATHOGENESIS OF DELAY OF INTRAUTERINE FETUS GROWTH

Abstract

The review is devoted to a problem of the intrauterine growth restriction (IUGR). The possible role in a pathogenesis of IUGR of genetic forms of a thrombophilia and circulation of the anti-phospholipid antibodies causing a preeclampsia and placental failure to 30-50% of cases according to different authors is discussed. The approaches to diagnostics, treatment and forecasting of IUGR including use of a fetometry, cardiotocography, dopplerometry, a research of an immunoreactivity, parameters of a hemostasis and vascular growth factors are presented.

Keywords

• delay of intrauterine fetus growth
• thrombophilia
• antiphospholipid syndrome
• diagnosis
• forecasting