Biomolecules (Sep 2024)

Advances in Microbial Exopolysaccharides: Present and Future Applications

  • Huu-Thanh Nguyen,
  • Thuy-Trang Pham,
  • Phu-Tho Nguyen,
  • Hélène Le-Buanec,
  • Holy N. Rabetafika,
  • Hary L. Razafindralambo

DOI
https://doi.org/10.3390/biom14091162
Journal volume & issue
Vol. 14, no. 9
p. 1162

Abstract

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Microbial exopolysaccharides (EPSs) are receiving growing interest today, owing to their diversity in chemical structure and source, multiple functions, and immense potential applications in many food and non-food industries. Their health-promoting benefits for humans deserve particular attention because of their various biological activities and physiological functions. The aim of this paper is to provide a comprehensive review of microbial EPSs, covering (1) their chemical and biochemical diversity, including composition, biosynthesis, and bacterial sources belonging mainly to lactic acid bacteria (LAB) or probiotics; (2) their technological and analytical aspects, especially their production mode and characterization; (3) their biological and physiological aspects based on their activities and functions; and (4) their current and future uses in medical and pharmaceutical fields, particularly for their prebiotic, anticancer, and immunobiotic properties, as well as their applications in other industrial and agricultural sectors.

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