Архивъ внутренней медицины (Oct 2014)
ИЗБЫТОЧНАЯ МАССА ТЕЛА И ОЖИРЕНИЕ КАК ФАКТОРЫ РИСКА НЕАЛКОГОЛЬНОЙ ЖИРОВОЙ БОЛЕЗНИ ПЕЧЕНИ
Abstract
Article is devoted to the role of body overweight in development of non-alcoholic steatohepatitis. Authors provide information about adipokines, peroxisome proliferator-activated receptors, proinflammatory cytokines in pathogenesis of nonalcoholic steatohepatitis. Authors analyze and describe special features of clinical picture and diagnostics, and also prophylaxis and treatment ways (changes in lifestyle, decrease of weight, possibility of metformin, thiazolidinedione, statins, essential phospholipids, vitamin E, ursodeoxycholic acid and probiotics treatment).
Keywords