Медицинская иммунология (Jul 2014)

INVESTIGATION OF NATURAL INHIBITORY ACTIVITY OF BLOOD SERUM IN ACUTE LEUKEMIA PATIENTS

  • G. M. Chernousova,
  • N. К. Rodosskaya

DOI
https://doi.org/10.15789/1563-0625-2009-6-577-580
Journal volume & issue
Vol. 11, no. 6
pp. 577 – 580

Abstract

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Abstract. The article contains results of studying the natural inhibitory serum activity in the patients with acute leukemia. A correlation is revealed between a resistance to myelosuppressive therapy, and positive inhibitory reaction towards immunoglobulins M. Determination of IL-2, IL-4 levels, as well as sulfhydril (SH- ) groups and amounts of blast cells at initial stage of disease are of high importance for early diagnosis of drug resistance upon the disease onset.

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