Nature Communications (Jul 2020)
Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections
- Neneh Sallah,
- Wendell Miley,
- Nazzarena Labo,
- Tommy Carstensen,
- Segun Fatumo,
- Deepti Gurdasani,
- Martin O. Pollard,
- Alexander T. Dilthey,
- Alexander J. Mentzer,
- Vickie Marshall,
- Elena M. Cornejo Castro,
- Cristina Pomilla,
- Elizabeth H. Young,
- Gershim Asiki,
- Martin L. Hibberd,
- Manjinder Sandhu,
- Paul Kellam,
- Robert Newton,
- Denise Whitby,
- Inês Barroso
Affiliations
- Neneh Sallah
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Wendell Miley
- Viral Oncology Section, AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
- Nazzarena Labo
- Viral Oncology Section, AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
- Tommy Carstensen
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Segun Fatumo
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Deepti Gurdasani
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Martin O. Pollard
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Alexander T. Dilthey
- Institute of Medical Microbiology and Hospital Hygiene, Heinrich Heine University Düsseldorf
- Alexander J. Mentzer
- Wellcome Centre for Human Genetics, University of Oxford
- Vickie Marshall
- Viral Oncology Section, AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
- Elena M. Cornejo Castro
- Viral Oncology Section, AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
- Cristina Pomilla
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Elizabeth H. Young
- The Wellcome Sanger Institute, Wellcome Genome Campus
- Gershim Asiki
- African Population and Health Research Center
- Martin L. Hibberd
- London School of Hygiene & Tropical Medicine
- Manjinder Sandhu
- Department of Medicine, University of Cambridge
- Paul Kellam
- Department of Infectious Diseases, Imperial College London
- Robert Newton
- MRC/UVRI at the London School of Hygiene & Tropical Medicine
- Denise Whitby
- Viral Oncology Section, AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Leidos Biomedical Research Inc.
- Inês Barroso
- The Wellcome Sanger Institute, Wellcome Genome Campus
- DOI
- https://doi.org/10.1038/s41467-020-17696-2
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 13
Abstract
Disease prognosis after infection with Kaposi’s sarcoma-associated herpesvirus and Epstein-Barr Virus is highly variable. Here the authors carry out epidemiological and genetic analysis of a Ugandan cohort and suggest complex interactions may influence pathogenesis and transmission.
