Possibilities of obtaining and using hydrogel-based biomaterials for regeneration of human bone tissue

Abstract

Substitution of defects in various tissues, especially bone tissues, is a major challenge in modern medicine. There is currently no universal method of filling defects which has no drawbacks. Hydrogels are one of the promising groups of alloplastic materials. At present, you can obtain materials with various biological properties like natural extracellular matrix using various methods of chemical and physical modification. These biomaterials can be used as a means of delivering stem cells and bioactive substances to the defect zone. This literature review is devoted to the various aspects of preparation and use of hydrogel-based biological materials.

Keywords

• hydrogels
• tissue regeneration
• tissue engineering