Nature Communications (Dec 2019)

Pan-cancer molecular subtypes revealed by mass-spectrometry-based proteomic characterization of more than 500 human cancers

  • Fengju Chen,
  • Darshan S. Chandrashekar,
  • Sooryanarayana Varambally,
  • Chad J. Creighton

DOI
https://doi.org/10.1038/s41467-019-13528-0
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 15

Abstract

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Mass-spectrometry-based profiling can be used to stratify tumours into molecular subtypes. Here, by classifying over 500 tumours, the authors show that this approach reveals proteomic subgroups which cut across tumour types.