Frontiers in Endocrinology (Mar 2023)
Poor sleep pattern is associated with metabolic disorder during transition from adolescence to adulthood
- Dan Zhang,
- Dan Zhang,
- Dan Zhang,
- Dan Zhang,
- Yajuan Yang,
- Shuang Zhai,
- Shuang Zhai,
- Shuang Zhai,
- Shuang Zhai,
- Yang Qu,
- Yang Qu,
- Yang Qu,
- Yang Qu,
- Tingting Li,
- Tingting Li,
- Tingting Li,
- Tingting Li,
- Yang Xie,
- Yang Xie,
- Yang Xie,
- Yang Xie,
- Shuman Tao,
- Shuman Tao,
- Shuman Tao,
- Liwei Zou,
- Liwei Zou,
- Liwei Zou,
- Liwei Zou,
- Fangbiao Tao,
- Fangbiao Tao,
- Fangbiao Tao,
- Fangbiao Tao,
- Xiaoyan Wu,
- Xiaoyan Wu,
- Xiaoyan Wu,
- Xiaoyan Wu
Affiliations
- Dan Zhang
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Dan Zhang
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Dan Zhang
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Dan Zhang
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Yajuan Yang
- School of Nursing, Anhui Medical University, Hefei, Anhui, China
- Shuang Zhai
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Shuang Zhai
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Shuang Zhai
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Shuang Zhai
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Yang Qu
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Yang Qu
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Yang Qu
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Yang Qu
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Tingting Li
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Tingting Li
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Tingting Li
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Tingting Li
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Yang Xie
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Yang Xie
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Yang Xie
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Yang Xie
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Shuman Tao
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Shuman Tao
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Shuman Tao
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Liwei Zou
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Liwei Zou
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Liwei Zou
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Liwei Zou
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Fangbiao Tao
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Fangbiao Tao
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Fangbiao Tao
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Fangbiao Tao
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- Xiaoyan Wu
- Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, China
- Xiaoyan Wu
- MOE Key Laboratory of Population Health Across Life Cycle, Hefei, China
- Xiaoyan Wu
- NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Hefei, China
- Xiaoyan Wu
- Anhui Provincial Key Laboratory of Population Health and Aristogenics, Anhui Medical University, Hefei, China
- DOI
- https://doi.org/10.3389/fendo.2023.1088135
- Journal volume & issue
-
Vol. 14
Abstract
ObjectiveThe purpose of this study was to investigate whether sleep pattern is associated with metabolic disorders among young adults.MethodsWe measured sleep patterns using multiple sleep behaviors in an ongoing prospective cohort among college students (n = 1,151). At baseline, 729 college students provided fasting blood samples and human body morphological measurements for quantification of metabolic parameters. Then, 340 participants continued to take metabolic parameters measurements at a 2-year follow-up. Sleep patterns were defined by chronotype, sleep duration, insomnia, snoring, and daytime sleepiness. Metabolic scores were derived for four metabolic parameters including body mass index (BMI), waist circumference (WC), fasting blood sugar (FBG), and insulin. Multivariate linear regression model was applied to analyze the association between sleep pattern types and metabolic parameters and metabolic scores.ResultsIn the baseline survey, we found that a total of 41 (4.1%) participants had poor sleep patterns. Then, metabolic scores were significantly higher among college students with poor sleep patterns, compared with those who with healthy sleep patterns at baseline (1.00 ± 0.96 vs. 0.78 ± 0.72, p < 0.05) and 2-year follow-up (0.34 ± 0.65 vs. 1.50 ± 1.64, p < 0.05). After covariates were adjusted, poor sleep pattern (β = 0.22, 95% CI: 0.06~2.53, p = 0.001) was associated with elevated metabolic scores at the 2-year follow-up.ConclusionsThe elevated metabolic burden observed in college students with poor sleep patterns highlights the need to identify and address sleep problems in order to minimize the long-term impact on disease vulnerability.
Keywords
