Menetrier's Disease with Squamous Metaplasia in a Child with Long Term Disease Evolution: A Case Review

Abstract

Menetrier's Disease is a hypertrophied gastropathy rarely encountered in pediatric population presenting with protein loss. It has acute and self-limiting disease course in children. In our patient the disease had long duration of progression lasting over 3 years. Eight year old boy had presented with failure to thrive and hypoproteinemia. Endoscopically he found to have thickened gastric folds from which biopsy was taken. Histopathological examination showed typical microscopic features of Menetrier's disease with squamous metaplasia. The squamous metaplasia seen associated with Menetrier's disease has not been noticed before in a child. Clinical suspicion along with endoscopic biopsy and histopathological study is essential in diagnosis.

Keywords

• menetrier's disease
• pediatric
• squamous metaplasia