Animals (Dec 2022)

One Health: Animal Models of Heritable Human Bleeding Diseases

  • W. Jean Dodds

DOI
https://doi.org/10.3390/ani13010087
Journal volume & issue
Vol. 13, no. 1
p. 87

Abstract

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Animal models of human and animal diseases have long been used as the lynchpin of experimental and clinical research. With the discovery and implementation of novel molecular and nano-technologies, cellular research now has advanced to assessing signal transduction pathways, gene editing, and gene therapies. The contribution of heritable animal models to human and animal health as related to hemostasis is reviewed and updated with the advent of gene editing, recombinant and gene therapies.

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