PLoS ONE (Jan 2020)

Patterns of prescription of antipsychotics in Qatar.

  • Sami Ouanes,
  • Imen Becetti,
  • Suhaila Ghuloum,
  • Samer Hammoudeh,
  • Mena Shehata,
  • Hany Ghabrash,
  • Areej Yehya,
  • Hawra Al-Lawati,
  • Nora Al-Fakhri,
  • Huma Iram,
  • Nighat Ajmal,
  • Yassin Eltorki,
  • Hassen Al-Amin

DOI
https://doi.org/10.1371/journal.pone.0241986
Journal volume & issue
Vol. 15, no. 11
p. e0241986

Abstract

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ObjectiveEven though all guidelines recommend generally against antipsychotic polypharmacy, antipsychotic polypharmacy appears to be a very common practice across the globe. This study aimed to examine the prescription patterns of antipsychotics in Qatar, in comparison with the international guidelines, and to scrutinize the sociodemographic and clinical features associated with antipsychotic polypharmacy.MethodsAll the medical records of all the inpatients and outpatients treated by antipsychotics at the Department of Psychiatry-Hamad Medical Corporation (HMC) in Doha, Qatar (between October 2012 and April 2014) were retrospectively analyzed. We retrieved the available sociodemographic data, psychiatric features, and details on the medication history.ResultsOur sample consisted of 537 individuals on antipsychotics (2/3 were male; mean age 33.8±10.2 years), prescribed for a psychotic disorder in 57%, a mood disorder in 9.3%, and various other diagnoses in 33.7%. About 55.9% received one antipsychotic, 29.6% received two antipsychotics, and 14.5% received more than two antipsychotics. Polypharmacy was associated with younger age (p = 0.025), being single (pConclusionsAntipsychotic polypharmacy appears to be quite common in Qatar, as it is the case in many other countries, in contrast with most international recommendations. Studies are needed to explore the reasons behind this disparity.