Biomedicines (Jul 2023)

COVID-19-Related Myocarditis: Are We There Yet? A Case Report of COVID-19-Related Fulminant Myocarditis

  • Alessandro Pierri,
  • Giulia Gagno,
  • Alessandra Fluca,
  • Davide Radaelli,
  • Diana Bonuccelli,
  • Laura Giusti,
  • Michela Bulfoni,
  • Antonio P. Beltrami,
  • Aneta Aleksova,
  • Stefano D’Errico

DOI
https://doi.org/10.3390/biomedicines11082101
Journal volume & issue
Vol. 11, no. 8
p. 2101

Abstract

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There is increasing evidence of cardiac involvement in COVID-19 cases, with a broad range of clinical manifestations spanning from acute life-threatening conditions such as ventricular dysrhythmias, myocarditis, acute myocardial ischemia and pulmonary thromboembolism to long-term cardiovascular sequelae. In particular, acute myocarditis represents an uncommon but frightening complication of SARS-CoV-2 infection. Even if many reports of SARS CoV-2 myocarditis are present in the literature, the majority of them lacks histological confirmation of cardiac injury. Here, we report a case of a young lady, who died suddenly a few days after testing positive for SARS-CoV-2, whose microscopic and genetics features suggested a direct cardiac involvement compatible with fulminant myocarditis.

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