Frontiers in Neurology (Sep 2020)

Progressive Encephalomyelitis With Rigidity and Myoclonus With Thymoma: A Case Report and Literature Review

  • Yana Su,
  • Li Cui,
  • Mingqin Zhu,
  • Yixuan Liang,
  • Ying Zhang

DOI
https://doi.org/10.3389/fneur.2020.01017
Journal volume & issue
Vol. 11

Abstract

Read online

Progressive encephalomyelitis with rigidity and myoclonus (PERM) is part of the variant type of the Stiff Person Syndrome (SPS) and is a rare neurological disease. We report here a patient with PERM who had thymoma and was positive for anti-glutamic acid decarboxylase (anti-GAD) antibodies. Her symptoms improved after treatment with hormones and gamma globulin. We also summarized the literature review of patients with PERM accompanied by tumors reported.

Keywords