Fertility quality of life for female patients undergoing in vitro fertilization-embryo transfer and influencing factors

Abstract

Objective: To investigate the fertility quality of life (Ferti QoL) of female patients undergoing in vitro fertilization and embryo transfer (IVF-ET), and to explore the related influenced factors. Methods: The random sampling has been conducted to enroll subjects, and questionnaires (General Information, Fertility Quality of Life, Perceived Social Support Scale, Self-Rating Anxiety Scale and Self-rating Depression Scale) were performed in patients undergoing IVF-ET at Reproductive Medicine Center of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine during December 2018 to June 2019. Results: A total of 236 IVF-ET patients were recruited in the study, and the total score of Ferti QoL was (64.6±13.12). Multiple linear regression analysis indicated that longer years of infertility(β=-4.8769, P<0.001), more financial difficulties (β=-7.2121, P<0.001), male factor-infertility (β=-3.6523, P=0.038), more IVF-EF cycles (β=-6.8252, P<0.001) and heavy depression (β=-0.4413, P<0.001) were independent factors for low FetiQoL. While living in a town (P=0.0186), having high monthly income (P=0.0181) and high degree of family support (P<0.001) were independently positively correlated with FertiQoL. Conclusions: The female undergoing IVF-EF have a significantly lower FertiQoL score, and while residence, monthly income, and social support are significantly associated with FertiQoL.

Keywords

• |in vitro fertilization-embryo transfer|fertility quality of life|social support|anxiety|depression|influencing factors