Dietary Intervention during Weaning and Development of Food Allergy: What Is the State of the Art?

Alessandro Gravina; Francesca Olivero; Giulia Brindisi; Antonia Fortunata Comerci; Chiara Ranucci; Cinzia Fiorentini; Eleonora Sculco; Ethel Figliozzi; Laura Tudini; Viviana Matys; Daniela De Canditiis; Maria Grazia Piccioni; Anna Maria Zicari; Caterina Anania

doi:10.3390/ijms25052769

International Journal of Molecular Sciences (Feb 2024)

Dietary Intervention during Weaning and Development of Food Allergy: What Is the State of the Art?

Alessandro Gravina,
Francesca Olivero,
Giulia Brindisi,
Antonia Fortunata Comerci,
Chiara Ranucci,
Cinzia Fiorentini,
Eleonora Sculco,
Ethel Figliozzi,
Laura Tudini,
Viviana Matys,
Daniela De Canditiis,
Maria Grazia Piccioni,
Anna Maria Zicari,
Caterina Anania

Affiliations

Alessandro Gravina: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Francesca Olivero: Independent Researcher, 00161 Rome, Italy
Giulia Brindisi: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Antonia Fortunata Comerci: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Chiara Ranucci: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Cinzia Fiorentini: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Eleonora Sculco: Department of Translation and Precision Medicine, Sapienza University of Rome, 00161 Rome, Italy
Ethel Figliozzi: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Laura Tudini: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Viviana Matys: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Daniela De Canditiis: Institute of Applied Calculus-CNR Rome, 00185 Rome, Italy
Maria Grazia Piccioni: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Anna Maria Zicari: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy
Caterina Anania: Department of Maternal Infantile and Urological Science, Sapienza University of Rome, 00161 Rome, Italy

DOI: https://doi.org/10.3390/ijms25052769
Journal volume & issue: Vol. 25, no. 5
p. 2769

Abstract

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Food allergy (FA) affects approximately 6–8% of children worldwide causing a significant impact on the quality of life of children and their families. In past years, the possible role of weaning in the development of FA has been studied. According to recent studies, this is still controversial and influenced by several factors, such as the type of food, the age at food introduction and family history. In this narrative review, we aimed to collect the most recent evidence about weaning and its role in FA development, organizing the gathered data based on both the type of study and the food. As shown in most of the studies included in this review, early food introduction did not show a potential protective role against FA development, and we conclude that further evidence is needed from future clinical trials.

Published in International Journal of Molecular Sciences

ISSN: 1661-6596 (Print); 1422-0067 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Biology (General); Science: Chemistry
Website: http://www.mdpi.com/journal/ijms

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