Nature Communications (Mar 2022)

Spelling interface using intracortical signals in a completely locked-in patient enabled via auditory neurofeedback training

  • Ujwal Chaudhary,
  • Ioannis Vlachos,
  • Jonas B. Zimmermann,
  • Arnau Espinosa,
  • Alessandro Tonin,
  • Andres Jaramillo-Gonzalez,
  • Majid Khalili-Ardali,
  • Helge Topka,
  • Jens Lehmberg,
  • Gerhard M. Friehs,
  • Alain Woodtli,
  • John P. Donoghue,
  • Niels Birbaumer

DOI
https://doi.org/10.1038/s41467-022-28859-8
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 9

Abstract

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The authors record neural firing rates in a patient with ALS in completely locked-in state and show that the patient can modulate neural firing rates based on auditory feedback to select letters to form words and phrases to communicate his needs and experiences.