Iranian Journal of Psychiatry (Mar 2013)

Undiagnosed Bipolar Disorders in Patients with Major Depressive Episode: Iran's part of a Multicenter Cross-Sectional Study.

  • Seyed Ali Ahmadi Abhari,
  • Majid Sadeghi,
  • Seyed Mehdi Samimi Ardestani,
  • Yousef Semnani,
  • Gholamreza Mirsepassi,
  • Seyed Saeed Sadr,
  • Atefe Kamaloo,
  • Morvarid Ahadi,
  • Behin Pourmirza,
  • Elham Mir

Journal volume & issue
Vol. 8, no. 1

Abstract

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Bipolar spectrum disorders may often go undiagnosed or unrecognized. The aim of this study was to determine the proportion of bipolar disorder symptoms in Iranian patients with a major depressive episode.313 patients with a current DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders 4th ed. Text rev.) diagnosed with a major depressive episode entered this cross-sectional study. Thirty two items revised Hypomania/ mania Symptoms Checklist (HCL-32) was used to determine the frequency of bipolar episodes.Considerable proportion of patients (53.9%) previously diagnosed as major depressive disorder fulfilled the criteria for bipolar disorder by Bipolarity Specifier. The Bipolarity Specifier additionally identified significant association for manic / hypomanic states during antidepressants therapy (p

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