A device for exposure to a permanent magnetic field and a system multifactorial analysis in a magnetobiological experiment

Abstract

Background. Interest in the biological effects of electromagnetic radiation on biological objects is associated with the possibility of their use in solving a number of fundamental and applied problems: from the consideration of biological feedbacks in real time, which allows the development of electronic medical complexes, to the creation of neuro-computer interfaces, including components of living cells. Aim. The paper shows the development of a device for influencing biological objects with a permanent magnetic field, which allows modeling the basic parameters of the physical factor, for conducting a magnetobiological experiment with normalization of the effects of non-ionizing radiation of the specified parameters. Methods. The device for influencing biological objects of constant magnetic field allows to obtain, in a large volume, the most homogeneous magnetic field. Results. Mathematical modeling of changes in the morphofunctional state of the adrenal cortex according to eleven biological parameters at different periods of exposure to normalized constant magnetic field when exposed to the maximum permissible level was evaluated by the deviation of the interval indicator and its normalized value. The effect of this factor led to a deviation of the integral index in the glomerular zone of the adrenal glands on the 30th day was – 6,53 ± 1,30*10-2, later on the 60th day the deviation increased by 8,28 ± 1,55*10-2, on the 90th 4,84 ± 1,50*10-2, then on the 120th day, it did not differ from normalized. Conclusion. After the termination of the constant magnetic field in a series of 15–30 mT experiments, the morphofunctional state of the thymus returned to normal. Thus, the device is recommended for use in experimental activities.

Keywords

• effects of magnetic fields
• multifactorial analysis
• magnetobiological experiment