860 Targeting immunosuppressive macrophages overcomes PARP-inhibitor resistance in BRCA1-associated triple-negative breast cancer

• Elizabeth Mittendorf,
• Jennifer Guerriero,
• Peter Sorger,
• Nadine Tung,
• Anita Mehta,
• Emily Cheney,
• Christina Hartl,
• Constantia Pantelidou,
• Madison Oliwa,
• Jessica Castrillon,
• Jia-Ren Lin,
• Mateus de Oliveira Taveira,
• Nathan Johnson,
• William Oldham,
• Marian Kalocsay,
• Matthew Berberich,
• Sarah Boswell,
• Aditi Kothari,
• Shawn Johnson,
• Deborah Dillon,
• Mikel Lipschitz,
• Scott Rodig,
• Sandro Santagata,
• Judy Garber,
• José Yélamos,
• Geoffrey Shapiro

Affiliations

Elizabeth Mittendorf

Aff2 grid.267308.80000000092062401MD Anderson Cancer CenterUniversity of Texas Houston TX USA

Jennifer Guerriero

1Dana Farber Cancer Institute, Boston, MA, USA

Peter Sorger

Aff4 000000041936754Xgrid.38142.3cHarvard Medical School-Harvard University Boston MA USA

Nadine Tung

8Beth Israel Deaconess Medical Center, Boston, MA, USA

Anita Mehta

1Dana Farber Cancer Institute, Boston, MA, USA

Emily Cheney

1Dana Farber Cancer Institute, Boston, MA, USA

Christina Hartl

1Dana Farber Cancer Institute, Boston, MA, USA

Constantia Pantelidou

1Dana Farber Cancer Institute, Boston, MA, USA

Madison Oliwa

2Dana-Farber Cancer Institute and Harvard, Boston, USA

Jessica Castrillon

1Dana Farber Cancer Institute, Boston, MA, USA

Jia-Ren Lin

3Harvard Medical School, Boston, MA, USA

Mateus de Oliveira Taveira

5A.C. Camargo Cancer Center, São Paulo, Brazil

Nathan Johnson

3Harvard Medical School, Boston, MA, USA

William Oldham

6Brigham and Women’s Hospital and Harvard, Boston, MA, USA

Marian Kalocsay

3Harvard Medical School, Boston, MA, USA

Matthew Berberich

3Harvard Medical School, Boston, MA, USA

Sarah Boswell

3Harvard Medical School, Boston, MA, USA

Aditi Kothari

1Dana Farber Cancer Institute, Boston, MA, USA

Shawn Johnson

1Dana Farber Cancer Institute, Boston, MA, USA

Deborah Dillon

7Brigham and Women’s Hospital and Harvard, Boston, MA, USA

Mikel Lipschitz

7Brigham and Women’s Hospital and Harvard, Boston, MA, USA

Scott Rodig

7Brigham and Women’s Hospital and Harvard, Boston, MA, USA

Sandro Santagata

7Brigham and Women’s Hospital and Harvard, Boston, MA, USA

Judy Garber

1Dana Farber Cancer Institute, Boston, MA, USA

José Yélamos

9Medical Research Institute, Barcelona, Spain

Geoffrey Shapiro

1Dana Farber Cancer Institute, Boston, MA, USA