Sustainable and efficient 2,3-dihydroquinazolin-4(1H)-ones production over heterogeneous and recyclable Al-MCM-41 supported dual imidazolium ionic liquids nanocomposites

Abstract

A type of Al-MCM-41 supported dual imidazolium ionic liquids nanocomposites have been synthesized and efficiently used as catalysts in the one-pot synthesis of 2,3-dihydroquinazolin-4(1H)-ones. It was shown that the highest efficiency was achieved in the condensation of a range of aldehydes and anthranilamide in the presence of the (2)Al-MCM-41@ILCeCl4(0.5) solid catalyst under mild conditions. Hot filtration test confirmed that the reaction follows a heterogeneous pathway. Moreover, the catalyst was stable, very active, robust, and displayed good recyclability without significant loss of catalytic activity after five consecutive cycles during the process. Green reaction conditions, operational simplicity, feasibility, high to excellent yields, sustainability of the functionalized catalyst are the main highlights of the present protocol.

Keywords

• Supported ionic liquids
• Mesoporous Al-MCM-41
• Heterogeneous catalysis
• 2,3-Dihydroquinazolin-4(1H)-ones
• Sustainability