Проблемы особо опасных инфекций (Jun 2011)

Genotypes and Subtypes of Hepatitis B Virus Isolates in the Territory of Siberia

  • G. V. Kochneva,
  • V. A. Manuylov,
  • I. G. Netesova,
  • E. V. Chub,
  • R. B. Bayandin,
  • G. F. Sivolobova,
  • A. A. Grazhdantseva,
  • S. V. Netesov

DOI
https://doi.org/10.21055/0370-1069-2011-3(109)-31-35
Journal volume & issue
Vol. 0, no. 3(109)
pp. 31 – 35

Abstract

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Identified are the occurrence, serotypic and genotypic variations of Hepatitis B virus isolates (HBV) among the Novosibirsk region inhabitants (n=2000), native population of the Alarsk District of the Irkutsk Region (n=487) and Shuryshkarsk Township of the Yamalo-Nenets Autonomous District (n=657). Occurrence rate of hepatitis В surface antigen (HBsAg) among different groups of the Novosibirsk Region population varied within the limits of 3,6-35,0 %. It was 8,2 % in Alarsk District, and 3,2 % in Shuryshkarsk Township. HBV isolates of D genotype (92-97 %) prevail among the population of Siberia; few are the cases of A (1,7 %) and C (1,2-8 %) genotypes. The identified varying occurrence of HBV sub-genotypes and HBsAg subtypes in two aboriginal groups of Siberia (D3 sub-genotype and ayw2 subtype - in the Alarsk District, D2 and ayw3 - in Shuryshkarsk Township) suggests the existence of, at least, two isolated HBV virus populations, circulating among different groups of Siberia native population .

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