Chemical fixation creates nanoscale clusters on the cell surface by aggregating membrane proteins

Affiliations

Takehiko Ichikawa: Nano Life Science Institute (WPI-NanoLSI), Kanazawa University
Dong Wang: Nano Life Science Institute (WPI-NanoLSI), Kanazawa University
Keisuke Miyazawa: Nano Life Science Institute (WPI-NanoLSI), Kanazawa University
Kazuki Miyata: Nano Life Science Institute (WPI-NanoLSI), Kanazawa University
Masanobu Oshima: Nano Life Science Institute (WPI-NanoLSI), Kanazawa University
Takeshi Fukuma: Nano Life Science Institute (WPI-NanoLSI), Kanazawa University

Abstract

Atomic force microscopy imaging shows that cell fixation can lead to unwanted aggregation of membrane proteins.