Revista da Sociedade Brasileira de Medicina Tropical (Jan 2020)

Acute disseminated encephalomyelitis (ADEM) associated with mosquito-borne diseases: Chikungunya virus X yellow fever immunization

  • Karolyna Carvalho,
  • Ana Luiza Biancardi,
  • Giovanna Provenzano,
  • Haroldo Moraes Jr

DOI
https://doi.org/10.1590/0037-8682-0160-2019
Journal volume & issue
Vol. 53

Abstract

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Abstract Acute disseminated encephalomyelitis (ADEM) is a demyelinating autoimmune neuropathic condition characterized by extensive bilateral and confluent lesions in the cerebral white matter and cerebellum. The basal ganglia and gray matter may also be involved. In most cases, the symptoms are preceded by viral infection or vaccination. In this report, we present a case of ADEM associated with optic neuritis presenting alongside two potential triggering factors: chikungunya virus infection and yellow fever immunization.

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