Immunopathological Mechanisms Underlying Cardiac Damage in Chagas Disease

Abstract

In Chagas disease, the mechanisms involved in cardiac damage are an active field of study. The factors underlying the evolution of lesions following infection by Trypanosoma cruzi and, in some cases, the persistence of its antigens and the host response, with the ensuing development of clinically observable cardiac damage, are analyzed in this review.

Keywords

• immunopathology
• zoonotic disease
• <i>Trypanosoma cruzi</i>
• Chagas disease
• cardiopathy