BMC Pregnancy and Childbirth (Mar 2022)

Massive ascites due to lupus peritonitis in a patient with pre-eclampsia and systemic lupus erythematosus: a case report

  • Shunya Sugai,
  • Kazuaki Suda,
  • Kana Tamegai,
  • Kazufumi Haino,
  • Takeshi Nakatsue,
  • Ichiei Narita,
  • Takayuki Enomoto,
  • Koji Nishijima

DOI
https://doi.org/10.1186/s12884-022-04550-0
Journal volume & issue
Vol. 22, no. 1
pp. 1 – 5

Abstract

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Abstract Background Patients with systemic lupus erythematosus (SLE) are associated with pre-eclampsia. Pre-eclampsia can have systemic manifestations, such as ascites. Lupus peritonitis, a rare condition in patients with SLE, can also cause ascites. Case presentation A 31-year-old woman, primigravida, with SLE had a blood pressure of 170/110 mmHg and proteinuria at 29 weeks of gestation. She was diagnosed with pre-eclampsia. Her blood pressure was stabilized by an antihypertensive drug. At 30 weeks of gestation, a cesarean section was performed for maternal safety because of decreased urine output and massive ascites. Postoperatively, re-accumulation of ascites was observed. On the fourth postoperative day, ascites (approximately 3 L) was discharged from the cesarean section wound. A decrease in serum complement concentrations was observed, and she was diagnosed as having lupus peritonitis. The steroid dose was increased and she recovered well thereafter. Conclusions Ascites occurs in pre-eclampsia and SLE, but determining which of these conditions causes ascites can be difficult. However, careful observation is necessary because of the differences in treatment of these two conditions.

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