Nature Communications (Sep 2017)

Genome-wide association and HLA region fine-mapping studies identify susceptibility loci for multiple common infections

  • Chao Tian,
  • Bethann S. Hromatka,
  • Amy K. Kiefer,
  • Nicholas Eriksson,
  • Suzanne M. Noble,
  • Joyce Y. Tung,
  • David A. Hinds

DOI
https://doi.org/10.1038/s41467-017-00257-5
Journal volume & issue
Vol. 8, no. 1
pp. 1 – 13

Abstract

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Susceptibility to infectious diseases is, among others, influenced by the genetic landscape of the host. Here, Tian and colleagues perform genome-wide association studies for 23 common infections and find 59 risk loci for 17 of these, both within the HLA region and non-HLA loci.