Determining complex aggregate distributions of macromolecules using photobleaching image correlation microscopy

Abstract

Aggregation of cell surface receptors is believed to be linked to their biological function. In this paper, we disclose the explicit formulation for macromolecular aggregation distribution by means of photobleaching Image Correlation Spectroscopy (pbICS).

Keywords

• Photobleaching ICS
• Aggregation Distribution
• Spatial Autocorrelation