Physical Activity Review (Nov 2016)

Intermittent fasting and its influence on health

  • Ivan Uher,
  • Zuzana Kűchelová,
  • Iveta Cimboláková,
  • Ján Pivovarník

DOI
https://doi.org/10.16926/par.2016.04.23
Journal volume & issue
Vol. 4
pp. 184 – 191

Abstract

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Food addiction is today the major cause of disease and death in our society and other economically developed countries. Hypothetically, this problem could be solved by simply convey the consequences of overeating to professionals and public. In reality though, it has been greatly difficult to successfully execute prolonged dietary restriction regimens. In context of the non-ability of many people to reduce their food intake, research pursuit are in progression to identify ways to alternatively reduce food intake or imitating the beneficial effects of dietary restriction using medical products, dietary supplements and gene therapies. Although allcells in the body require energy to last and perform efficiently, excessive calorie intake over long period of time can modify cell function and promote susceptibility to disease. In this review article we describe evidence suggesting that intermittent fasting (IF), can prolong the health through multiple interactive pathways and molecular mechanisms, all of which help cells cope with stress and resist disease. A better understanding of the impact of IF on the health will likely lead to novel approaches for preventing and treating numerous health disorders.

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